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HRID 2282作成日：2026年10月24日

Acetic Anhydride → N-[6-[2-{6-(4-tert-butylphenylsulfonylamino)-5-(4-methylphenyl)pyrimidin-4-yloxy}ethoxy]pyridin-3-yl]-acetamide

https://huagongshe.com/ja/reaction/2282

反応式

関与物質

役割名称HCID仕込み量
反応物Acetic AnhydrideHCID 7918—
反応物N-{6-{2-(5-aminopyridin-2-yloxy)ethoxy}-5-(4-methylphenyl)pyrimidin-4-yl}-4-tert-butylbenzenesulfonamideHCID 19689480—
生成物N-[6-[2-{6-(4-tert-butylphenylsulfonylamino)-5-(4-methylphenyl)pyrimidin-4-yloxy}ethoxy]pyridin-3-yl]-acetamideHCID 19689526—

反応手順

N-{6-{2-(5-Aminopyridin-2-yloxy)ethoxy}-5-(4-methylphenyl)pyrimidin-4-yl}-4-tert-butylbenzenesulfonamide and acetic anhydride are treated in the same manner as in Example 135 to give N-[6-[2-{6-(4-tert-butylphenylsulfonylamino)-5-(4-methylphenyl)pyrimidin-4-yloxy}ethoxy]pyridin-3-yl]-acetamide.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US05728706
出典データセットuspto-grants-1998_03
ORD IDord-2b27766230944f8c824648b85c6e1690
出典メモuspto-grants-1998_03