Water → HCID 53970235、化合物

HRID 2285432

反応式

HRID 2285432 の反応式
[CH3:1][O:2][C:3](=[O:12])[NH:4][C:5]1[CH:10]=[CH:9][CH:8]=[C:7](O)[CH:6]=1.C(N([CH2:18][CH3:19])CC)C.[OH2:20]>CC(C)=O>[C:3](=[O:2])([O:20][C:19]1[CH:18]=[CH:7][CH:6]=[CH:5][C:10]=1[C:7]1[CH:8]=[CH:9][CH:10]=[C:5]([NH:4][C:3]([O:2][CH3:1])=[O:12])[CH:6]=1)[NH2:4]

参加物

5

反応物 3

HCID 962WaterHCID 8471TriethylamineHCID 26181Methyl (3-hydroxyphenyl)-carbamate

生成物 1

HCID 53970235HCID 53970235、化合物

試薬・触媒・溶媒 1

HCID 180Acetone溶媒

実験手順

4.3 g (0.025 moles) of methyl-(N-3-hydroxyphenyl)-carbamate are reacted with 7.3 g (0.025 moles) of N-phenylcarbamoylbenzoic acid sulfimide (m.p.: 184°-186° C.) in 15 ml of acetone, in the presence of 2.56 g (0.025 moles) of triethyl amine, at 40° C. for 15 minutes. To the reaction mixture 40 ml of water are added and it is cooled to 5° to 10° C. The mixture is allowed to stand for 30 minutes, filtered, washed and dried. 5.5 g of 3-methoxycarbonylaminophenyl-phenyl carbamate are obtained, melting at 150° to 152° C.

後処理

  1. temperatureit is cooled to 5° to 10° C
  2. filtrationfiltered
  3. washwashed
  4. customdried

出典と根拠

ORDレコード
ord-11c258f730fb48a78e8f9517d290ae8c
出典データセット
uspto-grants-1982_04
特許番号
US04323469

関連ノート

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