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Epibromohydrin → 8-Phenyloctyloxymethyloxirane
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Epibromohydrin | HCID 18430 | — |
| 反応物 | Sodium hydride | HCID 24758 | — |
| 反応物 | 8-Phenyloctan-1-ol | HCID 517850 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | 8-Phenyloctyloxymethyloxirane | HCID 21474710 | — |
反応手順
A procedure similar to that described in Preparation 46 was repeated, except that 4 g of 8-phenyloctyl alcohol, 3.18 ml of epibromohydrin, 0.85 g of sodium hydride (as a 55% by weight dispersion in mineral oil) and 80 ml of anhydrous dimethylformamide were used, to give 2.42 g of the title compound having an Rf value of 0.51 (on silica gel thin layer chromatography, using a 1:6 by volume mixture of ethyl acetate and hexane as the developing solvent).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05688823 |
| 出典データセット | uspto-grants-1997_11 |
| ORD ID | ord-10af86dee11b4b3ea5b745844875f7d8 |
| 出典メモ | uspto-grants-1997_11 |