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2-Naphthaleneacetic acid → N-[(2-naphthyl)acetyl]-L-alanine Iso-butyl Ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Naphthaleneacetic acid | HCID 11393 | — |
| 反応物 | 2-Methylpropyl (2S)-2-aminopropanoate hydrochloride | HCID 86584981 | — |
| 生成物 | N-[(2-naphthyl)acetyl]-L-alanine Iso-butyl Ester | HCID 15481768 | — |
反応手順
Following General Procedure BB and using 2-naphthylacetic acid (Aldrich) and L-alanine iso-butyl ester hydrochloride (from Example BB above), the title compound was prepared as a solid having a melting point of 128°-129° C. The reaction was monitored by tlc on silica gel and purification was by extraction with Et2O followed by washes with aqueous K2CO3 and aqueous HCl.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06849650B2 |
| 出典データセット | uspto-grants-2005_02 |
| ORD ID | ord-c9209506e3fc498782b9f156ed5551cc |
| 出典メモ | uspto-grants-2005_02 |