化工社化工社 化学情報印刷レポート · 研究参考用
Sodium methanolate methanol → 3-Bromo-2-methoxy-6-methyl-pyridine 1-oxide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sodium methanolate methanol | HCID 23694274 | — |
| 反応物 | 3-Bromo-2-chloro-6-methylpyridin-1-ium-1-olate | HCID 85706489 | — |
| 生成物 | 3-Bromo-2-methoxy-6-methyl-pyridine 1-oxide | HCID 67001239 | — |
反応手順
step b—A solution of 357a (0.5 g) and 0.5 M NaOMe/MeOH (4.9 mL) was stirred at RT overnight. The reaction mixture was concentrated in vacuo and the residue loaded on a SiO2 column and eluted with 5% MeOH/DCM to afford 3-bromo-2-methoxy-6-methyl-pyridine 1-oxide (357b).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08273773B2 |
| 出典データセット | uspto-grants-2012_09 |
| ORD ID | ord-73430532814b4d63a3ab6aae8774a2c9 |
| 出典メモ | uspto-grants-2012_09 |