化工社化工社 化学情報印刷レポート · 研究参考用
Hydrochloric Acid → 2-[(7-Methoxy-1,2,3,4-tetrahydronaphth-2-yl)amino]-1-phenylethanol hydrochloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | Styrene | HCID 7501 | — |
| 反応物 | Ethyl Acetate | HCID 8857 | — |
| 反応物 | 2-Amino-7-methoxytetralin | HCID 11608015 | — |
| 溶媒 | Isopropanol | HCID 3776 | — |
| 生成物 | 2-[(7-Methoxy-1,2,3,4-tetrahydronaphth-2-yl)amino]-1-phenylethanol hydrochloride | HCID 20160885 | 31% |
反応手順
An amount of 3.01 g of 2-amino-7-methoxy-1,2,3,4-tetrahydronaphthalene is reacted under stirring at room temperature for 4 days with 2.04 g of styrene. After addition of ethyl acetate, to the reaction mixture there is added a saturated solution of hydrogen chloride in isopropyl alcohol to obtain the 2-[(7-methoxy-1,2,3,4-tetrahydronaphth-2-yl)amino]-1-phenylethanol hydrochloride. Yield: 31% of the theoretical value.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04707497 |
| 出典データセット | uspto-grants-1987_11 |
| ORD ID | ord-c6ec949ed93a401b858d43f2be35fd1a |
| 出典メモ | uspto-grants-1987_11 |