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Methyl iodide → 1-Methyl-2-[[[4-(tetradecyloxy)benzoyl]amino]methyl]pyridinium iodide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methyl iodide | HCID 6328 | — |
| 反応物 | N-(2-Pyridinylmethyl)-4-(tetradecyloxy)benzamide | HCID 10093859 | — |
| 生成物 | 1-Methyl-2-[[[4-(tetradecyloxy)benzoyl]amino]methyl]pyridinium iodide | HCID 10076647 | — |
反応手順
A mixture of 1.0 g of product from Example 4 and 7.33 ml of methyl iodide is heated, in a dark sealed tube, at 100°-120° C. for 22 hours. The cooled reaction mixture is concentrated in vacuo and recrystallized 2 times from methyl alcohol to give 1.15 g of the desired product as light yellow microneedles.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05208247 |
| 出典データセット | uspto-grants-1993_05 |
| ORD ID | ord-11dd4be9d0de4e58bbf14c8c3fe5d2bb |
| 出典メモ | uspto-grants-1993_05 |