関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Phosphorus tribromide | HCID 24614 | — |
| 反応物 | (2,2,5,5-Tetramethylcyclopentyl)methanol | HCID 13629260 | — |
| 溶媒 | Benzene | HCID 241 | — |
| 生成物 | 2,2,5,5-Tetramethyl-1-cyclopentylmethylbromide | HCID 13629261 | — |
反応手順
2,2,5,5-Tetramethyl-1-cyclopentylmethanol is dissolved in benzene and stirred at 0° C. under argon. A solution of phosphorus tribromide in benzene is added and the mixture is stirred for 2 hours and then heated to 60° C. for 4 hours. The mixture is cooled, poured into ice and extracted with ether. The organic layer is washed with saturated NaHCO3, dried over MgSO4 and evaporated to yield 2,2,5,5-Tetramethyl-1-cyclopentylmethyl bromide.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04701552 |
|---|
| 出典データセット | uspto-grants-1987_10 |
|---|
| ORD ID | ord-27fda164bd944f3e8b3098fcd207b707 |
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| 出典メモ | uspto-grants-1987_10 |
|---|
