関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Glycolic Acid | HCID 757 | — |
| 反応物 | 2-ethylhexanoic acid tin(II) salt | HCID 9318 | — |
| 反応物 | epsilon-CAPROLACTONE | HCID 10401 | — |
| 反応物 | Glycolide | HCID 65432 | — |
| 生成物 | Poliglecaprone | HCID 65431 | — |
反応手順
ε-Caprolactone (57.1 g, 0.5 mole), glycolide (1.1 g, 9.5 mole), glycolic acid (7.6 g, 0.1 mole) and stannous octoate (0.5 ml of 0.1M solution in toluene, 20 mg, 5×10-5 mole) were added to a glass reactor. The reactor was purged with dry nitrogen gas. The reactor was heated in an oil bath at 180° C. under nitrogen for 12 hours, while the contents were magnetically stirred. The final composition was determined by 1H NMR is shown to be essentially the same as the theoretical. The Tm is -62° C., and the Tg is 37° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05522842 |
|---|
| 出典データセット | uspto-grants-1996_06 |
|---|
| ORD ID | ord-a6a7c0223c554eceb3a3605fe6897a0e |
|---|
| 出典メモ | uspto-grants-1996_06 |
|---|
