関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Acetone | HCID 180 | — |
| 反応物 | Hydroxide | HCID 961 | — |
| 反応物 | Chlorobenzene | HCID 7964 | — |
| 反応物 | Acetic acid, cyclopent-2-en-1-yl ester | HCID 140735 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | Cyclopentanol, acetate | HCID 70273 | 96% |
反応手順
A solution of 1.80 g (0.014 mol) of 2-cyclopentenyl acetate in 3.80 g (0.12 mol) of methanol and 0.700 g of chlorobenzene (the internal standard for chromatographic analysis) was slowly passed through a jacketed column containing 20 ml of Dowex 1-X4 (an anion exchange resin of the quaternary ammonium type) in the hydroxide form in methanol. The column was maintained at 56° C. by refluxing acetone in the jacket. The resin was then rinsed with methanol, and the combined effluent and rinsings were analyzed by gas chromatography using a 6-ft. OV-17 column programmed from 80° to 220° C. The analysis showed that 2-cyclopentenol had been formed in 96% yield and essentially 100% efficiency. No by-products were observed.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04156097 |
|---|
| 出典データセット | uspto-grants-1979_05 |
|---|
| ORD ID | ord-5911146e230d4528b94a170bd145a9dd |
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| 出典メモ | uspto-grants-1979_05 |
|---|
