化工社化工社 化学情報印刷レポート · 研究参考用
Hydrochloric Acid → Nafimidone monohydrochloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | 2-(1H-Imidazol-1-yl)-1-(2-naphthalenyl)ethanone | HCID 51200 | — |
| 生成物 | Nafimidone monohydrochloride | HCID 51199 | — |
反応手順
Ethereal hydrogen chloride is added dropwise to a solution of 1.0 g. 1-(2-naphthoylmethyl)imidazole in 100 ml. anhydrous benzene until precipitation is complete. The product is filtered, washed with ether, air dried and recrystallized from methanol/acetone to yield 1-(2-naphthoylmethyl)imidazole hydrochloride, m.p. 226°-228.5° C. (decomp.)
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04150153 |
| 出典データセット | uspto-grants-1979_04 |
| ORD ID | ord-6ba27d46b2f5423ca8e9dc5ac6a8baa3 |
| 出典メモ | uspto-grants-1979_04 |