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n-(3-Aminopropyl)benzamide → 1-[1(2-((5-Methyl-4-imidazolyl)methylthio)ethylamino)-2-nitrovinylamino]-3-[N'-cyano-N"-(2-(2-pyridylmethylthio)ethyl)guanidino]propane
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | n-(3-Aminopropyl)benzamide | HCID 238993 | — |
| 反応物 | N-cyano-N'[2-(2-pyridylmethylthio)ethyl]-S-methylisothiourea | HCID 12889408 | — |
| 反応物 | 1-nitro-2-methylthio-2-{2-[(4-methyl-1H-imidazol-5-yl)methylthio]ethylamino}ethylene | HCID 70456864 | — |
| 生成物 | 1-[1(2-((5-Methyl-4-imidazolyl)methylthio)ethylamino)-2-nitrovinylamino]-3-[N'-cyano-N"-(2-(2-pyridylmethylthio)ethyl)guanidino]propane | HCID 178433675 | — |
反応手順
1-Nitro-2-methylthio-2-[2-((5-methyl-4-imidazolyl)methylthio)ethylamino]ethylene was reacted with 3-benzoylaminopropylamine and the product was hydrolysed under acidic conditions and reacted with N-cyano-N'-[2-(2-pyridylmethylthio)ethyl]-S-methylisothiourea to give the title compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04151289 |
| 出典データセット | uspto-grants-1979_04 |
| ORD ID | ord-89a7a9d8cd464c7daf04878ccf8298c1 |
| 出典メモ | uspto-grants-1979_04 |