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Dimethylformamide → Isatoic Anhydride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Dimethylformamide | HCID 6228 | — |
| 反応物 | Phthalamic acid | HCID 6957 | — |
| 反応物 | HCID 178418268 | HCID 178418268 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | Isatoic Anhydride | HCID 8359 | — |
反応手順
A 100 ml. flask was charged with 2.0 g. phthalamic acid suspended in 20 ml. dimethylformamide at room temperature. A 5.4 g. portion of lead tetra-acetate was added to the suspension, and the reaction mixture was held at room temperature for 40 minutes. The reaction mixture was poured into 30 ml. water. Isatoic anhydride was filtered from the water, recrystallized from dioxane, and dried in vacuo for 2 hours. The final yield of isatoic anhydride amounted to 1.07 g. tan solids, melting point 243°, and represented 54 percent of theory based on the phthalamic acid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US03947416 |
| 出典データセット | uspto-grants-1976_03 |
| ORD ID | ord-8509c51d2327474884dcb24775a06e1b |
| 出典メモ | uspto-grants-1976_03 |