化工社化工社 化学情報印刷レポート · 研究参考用
2-Fluoro-4-nitrotoluene → 2-(4-Amino-2-fluorophenyl)ethanol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Fluoro-4-nitrotoluene | HCID 74025 | — |
| 反応物 | Sodium Methoxide | HCID 10942334 | — |
| 溶媒 | Dimethyl Sulfoxide | HCID 679 | — |
| 生成物 | 2-(4-Amino-2-fluorophenyl)ethanol | HCID 45090600 | — |
反応手順
2-Fluoro-4-nitrotoluene and p-formaldehyde were allowed to undergo the reaction in DMSO in the presence of sodium methoxide, and then the resulting compound was subjected to catalytic hydrogenation in the same manner as shown in Reference Example 3 to obtain 3-fluoro-4-(2-hydroxyethyl)aniline. F: 156.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07449456B2 |
| 出典データセット | uspto-grants-2008_11 |
| ORD ID | ord-a0076cd7d98346488810ae7fab1d0183 |
| 出典メモ | uspto-grants-2008_11 |