化工社化工社 化学情報印刷レポート · 研究参考用
Ticlopidine → 4,5,6,7-Tetrahydrothieno(3,2-c)pyridine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ticlopidine | HCID 5472 | — |
| 反応物 | Thiopheneethanamine | HCID 116521 | — |
| 生成物 | 4,5,6,7-Tetrahydrothieno(3,2-c)pyridine | HCID 3085076 | — |
反応手順
Alternatively, ticlopidine of formula (1a) may also be synthesized by directly cyclizing 2-(2-aminoethyl)thiophene of formula (a) with a formylating agent to obtain 4,5,6,7-tetrahydrothieno[3,2-c]pyridine of formula (f), and then reacting the compound (f) with a compound of formula (b).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07449580B2 |
| 出典データセット | uspto-grants-2008_11 |
| ORD ID | ord-8918957f0be54d69b3276552a895d2b6 |
| 出典メモ | uspto-grants-2008_11 |