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Ethyl isothiocyanate → HCID 178465516、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ethyl isothiocyanate | HCID 10966 | — |
| 反応物 | HCID 178433288 | HCID 178433288 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | HCID 178465516 | HCID 178465516 | 86.4% |
反応手順
(i) A solution of 4-methyl-5-[(2-aminoethyl)thiomethyl]-imidazole (6.9 g.) and ethyl isothiocyanate (3.84 g.) in ethanol was heated under reflux for 2 hours. Concentration followed by recrystallisation of the residue from aqueous ethanol gave N-ethyl-N'-[2-((4-methyl-5-imidazolyl)methylthio)ethyl]thiourea (9.0 g.), m.p. 140°-141°. (Found: C, 46.5; H, 7.1; N, 21.7; S, 25.1. C10H18N4S2 requries: C, 46.5; H, 7.0; N, 21.7; S, 24.8).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04221802 |
| 出典データセット | uspto-grants-1980_09 |
| ORD ID | ord-eac2b735f3e4411fbacf8fbf900340f6 |
| 出典メモ | uspto-grants-1980_09 |