化工社化工社 化学情報印刷レポート · 研究参考用
Dichlorodimethylsilane → Chlorodimethyl(1,5,6,7-tetrahydro-3-phenyl-s-indacen-1-yl)silane
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Dichlorodimethylsilane | HCID 6398 | — |
| 反応物 | Lithium, mol. (Li2) | HCID 139759 | — |
| 反応物 | 1,2,3,5-Tetrahydro-7-phenyl-s-indacene | HCID 18628377 | — |
| 溶媒 | Tetrahydrofuran | HCID 8028 | — |
| 生成物 | Chlorodimethyl(1,5,6,7-tetrahydro-3-phenyl-s-indacen-1-yl)silane | HCID 18628376 | 91.1% |
反応手順
1,2,3,5-Tetrahydro-7-phenyl-s-indacene, dilithium salt (12.2075 g, 0.05102 moles) in THF (50 mL) was added dropwise to a solution of Me2SiCl2 (19.5010 g, 0.1511 moles) in THF (100 mL) at 0° C. This mixture was then allowed to stir at room temperature overnight. After the reaction period the volatiles were removed and the residue extracted and filtered using hexane. The removal of the hexane resulted in the isolation of the desired product as a yellow oil (15.1492 g, 91.1% yield).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06355341B1 |
| 出典データセット | uspto-grants-2002_03 |
| ORD ID | ord-ad7e872258d7426c8e40abcae79acf16 |
| 出典メモ | uspto-grants-2002_03 |