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Butanenitrile, 3-imino- → 1-(6-chloropyridazin-3-yl)-3-methyl-1H-pyrazol-5-amine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Butanenitrile, 3-imino- | HCID 70698 | — |
| 反応物 | 3-Chloro-6-hydrazinopyridazine | HCID 100787 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | 1-(6-chloropyridazin-3-yl)-3-methyl-1H-pyrazol-5-amine | HCID 6408845 | — |
反応手順
A mixture of 14.5 g (0.1 moles) of 3-chloro-6-pyridazinyl-hydrazine, 8.5 g (0.1 moles) of 3-iminobutyronitrile and 150 ml of ethanol is heated to reflux for 9 hours. After cooling the separated crystals are filtered, washed with ethanol and dried. Yield: 15.6 g (74.0%); m.p.: 148°-150° C. The hydrochloride melts at 157°-159° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04224325 |
| 出典データセット | uspto-grants-1980_09 |
| ORD ID | ord-f95930bf92b241b29b08fdf04c19328f |
| 出典メモ | uspto-grants-1980_09 |