p-(Trifluoromethoxy)benzenesulphonyl chloride → N-[4-Bromo-2-(pyridine-4-carbonyl)-phenyl]4-trifluoromethoxy-benzenesulfonamide

関与物質

反応手順

The title compound was prepared according to the general procedure for the synthesis of N-Aryl-benzenesulfonamides previously described using 138 mg of (2-Amino-5-bromo-phenyl)-pyridin-4-yl-methanone and 130 mg of 4-trifluoromethoxy-benzenesulfonyl chloride. 1H-NMR (400 MHz, CDCl3): δ 7.21 (d, 2H, J=8.8 Hz), 7.35 (m, 2H), 7.45 (s,1H), 7.70 (m, 2H), 7.83 (m, 2H), 8.82 (dd, 2H, J=4.8 Hz, 1.6 Hz), 10.21 (s, 1H). MS: m/z 502.3 (M++1).

情報源と証拠