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Hydrazine hydrate (1:1) → 7-Methoxy-4-phenylphthalazin-1(2H)-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrazine hydrate (1:1) | HCID 24654 | — |
| 反応物 | 2-Benzoyl-5-methoxybenzoic acid | HCID 334080 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | 7-Methoxy-4-phenylphthalazin-1(2H)-one | HCID 69214002 | 13.9% |
反応手順
10.55 g (210 mmol) of hydrazine hydrate are added to a solution of 5.4 g of 2-benzoyl-5-methoxy-benzoic acid in 50 mL of ethanol, and the mixture is refluxed for 2 hours 30 minutes. The reaction medium is cooled and then filtered. The precipitate obtained is washed with ethanol and then dried under reduced pressure at 40° C. 740 mg of product are obtained in the form of a white solid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07423030B2 |
| 出典データセット | uspto-grants-2008_09 |
| ORD ID | ord-e8f6f113ac9d4958b23dbe1a795271f7 |
| 出典メモ | uspto-grants-2008_09 |