化工社化工社 化学情報印刷レポート · 研究参考用
1-Chloro-2-fluoro-4-iodo-5-methoxybenzene → (2-Amino-6-chloro-pyridin-3-yl)-(4-chloro-5-fluoro-2-methoxy-phenyl)-methanone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-Chloro-2-fluoro-4-iodo-5-methoxybenzene | HCID 21070630 | — |
| 反応物 | 2-Amino-6-chloro-N-methoxy-N-methyl-nicotinamide | HCID 58590824 | — |
| 生成物 | (2-Amino-6-chloro-pyridin-3-yl)-(4-chloro-5-fluoro-2-methoxy-phenyl)-methanone | HCID 58590823 | — |
反応手順
The title compound was prepared from 2-Amino-6-chloro-N-methoxy-N-methyl-nicotinamide (Example 3) and 5-chloro-4-fluoro-2-iodoanisole (prepared as described in Step A above) using the procedure described in Example 7. HRMS, observed: 312.9943, Calcd for (M−H)+: 312.9947.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07423051B2 |
| 出典データセット | uspto-grants-2008_09 |
| ORD ID | ord-8b2ab23d421d4ca7b820de3c492a45e2 |
| 出典メモ | uspto-grants-2008_09 |