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1-(6-Chloropyridin-3-yl)ethan-1-one → 1-{6-[(2-{[4-(2,4-Dichlorophenyl)-5-imidazolylpyrimidin-2-yl]amino}-ethyl)amino]-3-pyridyl}ethan-1-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-(6-Chloropyridin-3-yl)ethan-1-one | HCID 2779698 | — |
| 反応物 | [4-(2,4-Dichlorophenyl)-5-imidazol-2-ylpyrimidin-2-yl]{2-[(6-methoxy-5-nitro(2-pyridyl)) amino]ethyl}amine | HCID 22142635 | — |
| 反応物 | 4-(2,4-Dichlorophenyl)-5-imidazol-1-ylpyrimidin-2-ylethylamine | HCID 57174895 | — |
| 生成物 | 1-{6-[(2-{[4-(2,4-Dichlorophenyl)-5-imidazolylpyrimidin-2-yl]amino}-ethyl)amino]-3-pyridyl}ethan-1-one | HCID 57208807 | — |
反応手順
1-{6-[(2-{[4-(2,4-dichlorophenyl)-5-imidazolylpyrimidin-2-yl]amino}ethyl)-amino]-3-pyridyl}ethan-1-one was prepared from [4-(2,4-dichlorophenyl)-5-imidazol-1-ylpyrimidin-2-yl]ethylamine and 1-(6-chloro-3-pyridyl)-ethanone (prepared as described in Tetrahedron 48:9233 (1992)) in accordance to the procedure described above for the preparation of [4-(2,4-dichlorophenyl)-5-imidazol-2-ylpyrimidin-2-yl]{2-[(6-methoxy-5-nitro(2-pyridyl))amino]ethyl}amine.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07425557B2 |
| 出典データセット | uspto-grants-2008_09 |
| ORD ID | ord-52330fd33fce41b5a6eeccffee9d0b7b |
| 出典メモ | uspto-grants-2008_09 |