化工社化工社 化学情報印刷レポート · 研究参考用
1-[3-(4-Hydroxy-3-methoxyphenyl)propyl]-1,2,4-triazole → 1-[3-[3-methoxy-4-[2-[(E)-2-phenylethenyl]-4-oxazolylmethoxy]phenyl]propyl]-1,2,4-triazole
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-[3-(4-Hydroxy-3-methoxyphenyl)propyl]-1,2,4-triazole | HCID 22009715 | — |
| 反応物 | 4-Chloromethyl-2-styryl-oxazole | HCID 22009752 | — |
| 生成物 | 1-[3-[3-methoxy-4-[2-[(E)-2-phenylethenyl]-4-oxazolylmethoxy]phenyl]propyl]-1,2,4-triazole | HCID 22009670 | 62% |
反応手順
In substantially the same manner as in Working Example 37, 1-[3-(4-hydroxy-3-methoxyphenyl)propyl]-1,2,4-triazole was allowed to react with 4-chloromethyl-2-[(E)-2-phenylethenyl]oxazole to give 1-[3-[3-methoxy-4-[2-[(E)-2-phenylethenyl]-4-oxazolylmethoxy]phenyl]propyl]-1,2,4-triazole. The yield was 62%. Recrystallization from ethyl acetate-hexane gave colorless prisms, mp 113-114° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06211215B1 |
| 出典データセット | uspto-grants-2001_04 |
| ORD ID | ord-f331cd630d6847788e012101965cc8b4 |
| 出典メモ | uspto-grants-2001_04 |