化工社化工社 化学情報印刷レポート · 研究参考用
Methanol → 2-Butyl-1,3-diazaspiro[4.4]non-1-en-4-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methanol | HCID 887 | — |
| 反応物 | N-(1-Cyanocyclopentyl)pentanamide | HCID 11790092 | — |
| 生成物 | 2-Butyl-1,3-diazaspiro[4.4]non-1-en-4-one | HCID 10176511 | — |
反応手順
To 19.6 g (0,1 mol) of 1-cyano-1-n-pentanoylaminocyclopentane dissolved in 70 ml of methanol, 5 g of Varion AD resin was added the reaction mixture was heated under reflux conditions for 3 hours. After filtration and evaporation 16.5 g (71.7%) of title compound was obtained, assay by GC: 92%.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06211382B1 |
| 出典データセット | uspto-grants-2001_04 |
| ORD ID | ord-0e035a38a6d2411897178fb37aeacd16 |
| 出典メモ | uspto-grants-2001_04 |