化工社化工社 化学情報印刷レポート · 研究参考用
Morpholine → 5-(Cyclopropylmethyl-sulfamoyl)-2-morpholin-4-yl-benzoic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Morpholine | HCID 8083 | — |
| 反応物 | 2-Chloro-5-(cyclopropylmethyl-sulfamoyl)-benzoic acid | HCID 29035580 | — |
| 反応物 | 5-Methanesulfonyl-2-pyrrolidin-1-yl-benzoic acid | HCID 59793489 | — |
| 生成物 | 5-(Cyclopropylmethyl-sulfamoyl)-2-morpholin-4-yl-benzoic acid | HCID 59793585 | 33% |
反応手順
The title compound was synthesised according to the procedure described for the synthesis of 5-Methanesulfonyl-2-pyrrolidin-1-yl-benzoic acid from 2-Chloro-5-(cyclopropylmethyl-sulfamoyl)-benzoic acid and morpholine and obtained in 33% yield. MS (m/e): 339.2 (MH−, 100%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07427612B2 |
| 出典データセット | uspto-grants-2008_09 |
| ORD ID | ord-11e7349391db427aa8f0b88c2e719f51 |
| 出典メモ | uspto-grants-2008_09 |