化工社化工社 化学情報印刷レポート · 研究参考用
Methanol → Methyl 3-iodo-5-nitrobenzoate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methanol | HCID 887 | — |
| 反応物 | Thionyl Chloride | HCID 24386 | — |
| 反応物 | 3-Iodo-5-nitrobenzoic acid | HCID 80580 | — |
| 生成物 | Methyl 3-iodo-5-nitrobenzoate | HCID 7020599 | 99% |
反応手順
To a solution of 3-iodo-5-nitrobenzoic acid (20.00 g, 0.068 mol) in methanol (50 mL) was added SOCl2 (5.45 mL, 0.075 mol) at 0° C. The reaction mixture was allowed to warm to room temperature and was then heated to breflux for 2 hours. The reaction was cooled and solvent was removed in vacuo to afford 3-Iodo-5-nitro-benzoic acid methyl ester as light yellow solid (20.67 g, 99%). MS (M+H)=309.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08895589B2 |
| 出典データセット | uspto-grants-2014_11 |
| ORD ID | ord-f432f7a953304c8eb4589c665dcee18c |
| 出典メモ | uspto-grants-2014_11 |