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Acetic Anhydride → 2,4-Dimethyl-6-(2-phenylacryloyl)phenol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Acetic Anhydride | HCID 7918 | — |
| 反応物 | 1-(2-Hydroxy-3,5-dimethylphenyl)-2-phenylethan-1-one | HCID 14025983 | — |
| 溶媒 | N,N,N',N'-Tetramethylmethanediamine | HCID 5829 | — |
| 生成物 | 2,4-Dimethyl-6-(2-phenylacryloyl)phenol | HCID 14873443 | — |
反応手順
212.6 Grams of 4,6-dimethyl-2-(2-phenylacetyl)phenol was dissolved in 350 ml of N,N,N',N'-tetramethyldiaminomethane, then under ice-cooled condition with stirring, 350 ml of acetic anhydride was added dropwise thereto. The reaction mixture was further stirred at room temperature for 2 hours, then was poured in 1 kg of ice and stirred vigorously. The crystals separated in the mixture were collected by filtration, washes with water, then dried. Recrystallized from ethanol to obtain 186 g of 2,4-dimethyl-6-(2-phenylacryloyl)phenol. Colorless needle-like crystals. Melting point: 83°-84° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05055474 |
| 出典データセット | uspto-grants-1991_10 |
| ORD ID | ord-f7b8def8bc9342b79bd336c8fdb40bb9 |
| 出典メモ | uspto-grants-1991_10 |