化工社化工社 化学情報印刷レポート · 研究参考用
7-(3-fluoro-benzyloxy)-2,3,4,5-tetrahydro-1H-benzo[d]azepine hydrochloride → HCID 11221548、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 7-(3-fluoro-benzyloxy)-2,3,4,5-tetrahydro-1H-benzo[d]azepine hydrochloride | HCID 21080184 | — |
| 反応物 | HCID 69291666 | HCID 69291666 | — |
| 溶媒 | Triethylamine | HCID 8471 | — |
| 生成物 | HCID 11221548 | HCID 11221548 | 88% |
反応手順
[7-(3-Fluoro-benzyloxy)-1,2,4,5-tetrahydro-benzo[d]azepin-3-yl]-oxo-acetic acid ethyl ester: The title compound was prepared in analogy to Example 1d) from 7-(3-fluoro-benzyloxy)-2,3,4,5-tetrahydro-1H-benzo[d]azepine hydrochloride [Example 1c)] and ethyl oxalic acid chloride with triethylamine as the base. Yield: 88% of theory as a colourless oil; MS: m/e=372 (M+H)+.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07173023B2 |
| 出典データセット | uspto-grants-2007_02 |
| ORD ID | ord-9c9c2595a27844f3a998bcc46fd854a8 |
| 出典メモ | uspto-grants-2007_02 |