化工社化工社 化学情報印刷レポート · 研究参考用
Methanol → Methyl 4-acetylbenzoate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methanol | HCID 887 | — |
| 反応物 | Sulfuric Acid | HCID 1118 | — |
| 反応物 | 4-Acetylbenzoic Acid | HCID 11470 | — |
| 生成物 | Methyl 4-acetylbenzoate | HCID 137990 | — |
反応手順
4-Acetylbenzoic acid (12.7 g., 0.077 mol) was dissolved in 750 ml. methanol. Concentrated H2SO4 (1.6 ml.) was added and the mixture heated at 70° for 8 hours, cooled, stripped solids, taken up in 400 ml. ether, washed 3×150 ml. saturated NaHCO3 and 1×150 ml. brine, dried over MgSO4 and stripped to yield title product, 12.9 g.; tlc Rf 0.46 (2:1 hexane:ethyl acetate).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04762921 |
| 出典データセット | uspto-grants-1988_08 |
| ORD ID | ord-fc6ba0155df54434845b93f9b793b887 |
| 出典メモ | uspto-grants-1988_08 |