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Tributyltin Chloride → 1H-Pyrrole-1-carboxylic acid, 2-(tributylstannyl)-, 1,1-dimethylethyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Tributyltin Chloride | HCID 15096 | — |
| 反応物 | tert-butyl 1H-pyrrole-1-carboxylate | HCID 643494 | — |
| 反応物 | HCID 86753332 | HCID 86753332 | — |
| 溶媒 | Tetrahydrofuran | HCID 8028 | — |
| 生成物 | 1H-Pyrrole-1-carboxylic acid, 2-(tributylstannyl)-, 1,1-dimethylethyl ester | HCID 11363059 | — |
反応手順
(1-(t-Butoxycarbonyl)pyrrol-2-yl)tributyltin LDA in dry THF (1.2M, 0.83 mL) was slowly added to a cooled (-78° C.) solution of 1-(t-butoxycarbonyl)pyrrole (0.67 g) in dry THF (5 mL). After stirring for 3 h, tributyltin chloride (0.65 g) was slowly added, and the mixture was allowed to warm to room temperature overnight. The solvent was removed to provide (1-(t-butoxycarbonyl)pyrrol-2-yl)tributyltin, suitable for use in the next reaction.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05837704 |
| 出典データセット | uspto-grants-1998_11 |
| ORD ID | ord-f8fd33df5b2b4687b7292d5d66b34ca6 |
| 出典メモ | uspto-grants-1998_11 |