化工社化工社 化学情報印刷レポート · 研究参考用
Triethylamine → HCID 53788593、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Triethylamine | HCID 8471 | — |
| 反応物 | Cyclopentene | HCID 8882 | — |
| 反応物 | 3-Iodobenzyl alcohol | HCID 42300 | — |
| 反応物 | Tri-o-tolylphosphine | HCID 80271 | — |
| 触媒 | palladium(II) acetate | HCID 167845 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | HCID 53788593 | HCID 53788593 | 232.3% |
反応手順
According to example 61, 10.0 g of 3-iodobenzyl alcohol (Aldrich) was treated with 30 mL of cyclopentene using 0.96 g of Pd(OAc)2, 2.60 g of tri-ortho-tolylphosphine, and 6.6 mL of Et3N. The resulting olefin mixture was hydrogenated for 2.5 h using 0.62 g of 5% Pt(C) in MeOH to afford 5.77 g (76%) of 3-cyclopentylbenzyl alcohol as a light yellow liquid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06140100 |
| 出典データセット | uspto-grants-2000_10 |
| ORD ID | ord-16b62740afed44928af8603f652819cf |
| 出典メモ | uspto-grants-2000_10 |