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2-(Chloromethyl)thiophene → (E)-4-[2-n-Butyl-1-{(2-chlorophenyl)methyl}-1H-imidazol-5-yl]-2-(2-thienyl)methyl-3-(2-thienyl)methyl-3-butenoic Acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-(Chloromethyl)thiophene | HCID 69830 | — |
| 反応物 | (E)-4-[2-n-butyl-1-{(2-chlorophenyl)methyl}-1H-imidazol-5-yl]-2-methyl-3-(2-thienyl)methyl-3-butenoic acid | HCID 70043244 | — |
| 生成物 | (E)-4-[2-n-Butyl-1-{(2-chlorophenyl)methyl}-1H-imidazol-5-yl]-2-(2-thienyl)methyl-3-(2-thienyl)methyl-3-butenoic Acid | HCID 70044041 | — |
反応手順
This compound is prepared according to the procedure of Example 14(i, ii) using less than one equivalent of 2-chloromethylthiophene in place of methyl iodide.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05418250 |
| 出典データセット | uspto-grants-1995_05 |
| ORD ID | ord-07ee8a774b9b4c79a8437c6eba64e690 |
| 出典メモ | uspto-grants-1995_05 |