3,4-Diethoxycarbonyl-5-nitro-6-phenyl-2-(1,2,4-triazol-1-yl)pyridine → HCID 15289701、化合物

関与物質

反応手順

In 25 ml of ethyl acetate was dissolved 0.35 g of 3,4-diethoxycarbonyl-5-nitro-6-phenyl-2-(1,2,4-triazol-1-yl)pyridine, whereto 0.2 g of 10% Pd-C (50% wet) was added. The mixture was stirred in a stream of hydrogen at room temperature for 2.5 hours. After the catalyst was removed by filtration, the filtrate was concentrated. The residue was subjected to silica gel column chromatography (eluent:chloroform/ethyl acetate 4:1), to give 0.215 g of the title compound.

情報源と証拠