関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Phenyl isocyanate | HCID 7672 | — |
| 反応物 | 5-Amino-1-phenyl-1H-pyrazole-4-carbonitrile | HCID 79256 | — |
| 反応物 | Potassium tert-butoxide | HCID 23665647 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | 1-Phenyl-4-cyano-5-(phenylureido)-pyrazole | HCID 18993713 | 96% |
反応手順
9.0 g (80 mmol) of potassium tert-butylate and 8.7 ml (80 mmol) of phenyl isocyanate were added to a solution of 5.52 g (30 mmol) of 1-phenyl-4-cyano-5-aminopyrazole in 100 ml of toluene. The mixture was heated for 15 hours at 80° C. and then cooled, the insoluble constituents were separated off and the resulting solution was acidified with acetic acid, the product crystallizing out. Yield: 96%.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05486618 |
|---|
| 出典データセット | uspto-grants-1996_01 |
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| ORD ID | ord-d3008fed65aa48ba88f258b2fe528189 |
|---|
| 出典メモ | uspto-grants-1996_01 |
|---|
