関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | 2-Chloroquinoline | HCID 11928 | — |
| 反応物 | Hydrazine hydrate (1:1) | HCID 24654 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | Quinoline, 2-hydrazinyl- | HCID 85111 | — |
反応手順
21.0 g (128.4 mmol) of 2-chloroquinoline are initially charged in 210 ml of ethanol. 64.3 g (1.3 mol) of hydrazine hydrate are added, and the mixture is stirred under reflux for 16 h. The mixture is then cooled to 0° C., and the solid formed is filtered off and washed with a little ethanol. The product is initially air-dried and then dried under high vacuum.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US08524699B2 |
|---|
| 出典データセット | uspto-grants-2013_09 |
|---|
| ORD ID | ord-cfd11d007e1f473c91d1538a8a8ee657 |
|---|
| 出典メモ | uspto-grants-2013_09 |
|---|
