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1-Cyclohexyl-3-(2-morpholinoethyl)carbodiimide metho-p-toluenesulfonate → HCID 10514281、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-Cyclohexyl-3-(2-morpholinoethyl)carbodiimide metho-p-toluenesulfonate | HCID 17220 | — |
| 反応物 | 4,5-Dichloro-1,2-phenylenediamine | HCID 79297 | — |
| 反応物 | Cyclopropyl isothiocyanate | HCID 92463 | — |
| 溶媒 | Pyridine | HCID 1049 | — |
| 生成物 | HCID 10514281 | HCID 10514281 | 70.5% |
反応手順
4,5-Dichloro-1,2-phenylenediamine (6.04 g, 34.1 mmol), cyclopropyl isothiocyanate (3.69 g, 37.2 mmol), 1-cyclohexyl-3-(2-morpholinoethyl)carbodiimide metho-p-toluenesulfonate (20.1 g, 47.4 mmol) and pyridine (135 mL) were used according to general procedure I. The product was recrystallized from acetonitrile to afford 5.82 g (70%) of a yellow solid; m.p. 223-225° C. Anal. Calcd for C10H9Cl2N3: C, 49.61; H, 3.75; N, 17.36. Found: C, 49.53; H, 3.78; N, 17.12.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06307043B1 |
| 出典データセット | uspto-grants-2001_10 |
| ORD ID | ord-7822d9433a7a4c408cecd83ed668d803 |
| 出典メモ | uspto-grants-2001_10 |