化工社化工社 化学情報印刷レポート · 研究参考用
Benzilic acid → (1r/s,3r)-3-(2-Hydroxy-2,2-diphenyl-acetoxy)-1-methyl-1-(pyrazin-2-yl-carbamoyl-methyl)-pyrrolidinium bromide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Benzilic acid | HCID 6463 | — |
| 反応物 | HCID 131730243 | HCID 131730243 | — |
| 生成物 | (1r/s,3r)-3-(2-Hydroxy-2,2-diphenyl-acetoxy)-1-methyl-1-(pyrazin-2-yl-carbamoyl-methyl)-pyrrolidinium bromide | HCID 131730257 | — |
反応手順
This compound is prepared by an analogous method to (1R/S,3R)-3-((R/S)-(2-cyclohexyl-2-hydroxy-2-phenyl-acetoxy)-1-methyl-1-(pyrazin-2-ylcarbamoylmethyl)-pyrrolidinium bromide (Example 1) by replacing cyclohexyl-hydroxy-phenyl-acetic acid with benzilic acid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08383625B2 |
| 出典データセット | uspto-grants-2013_02 |
| ORD ID | ord-8332f730aa044703b7b98fdd89ac44b8 |
| 出典メモ | uspto-grants-2013_02 |