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N-methylpiperidine-4-carboxamide → 1-((2-chloro-4-morpholinothieno[2,3-d]pyrimidin-6-yl)methyl)-N-methylpiperidine-4-carboxamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | N-methylpiperidine-4-carboxamide | HCID 2760460 | — |
| 反応物 | 2-Chloro-4-morpholinothieno[2,3-d]pyrimidine-6-carbaldehyde | HCID 56833844 | — |
| 生成物 | 1-((2-chloro-4-morpholinothieno[2,3-d]pyrimidin-6-yl)methyl)-N-methylpiperidine-4-carboxamide | HCID 86623532 | — |
反応手順
Reaction between 2-chloro-4-morpholin-4-yl-thieno[2,3-d]pyrimidine-6-carbaldehyde (General Procedure D-2) and piperidine-4-carboxylic acid methylamide (Example 25) using General Procedure B-3 yielded 1-((2-chloro-4-morpholinothieno[2,3-d]pyrimidin-6-yl)methyl)-N-methylpiperidine-4-carboxamide.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08383620B2 |
| 出典データセット | uspto-grants-2013_02 |
| ORD ID | ord-a4c69477e29c4d60ba8b342627fe7d66 |
| 出典メモ | uspto-grants-2013_02 |