化工社化工社 化学情報印刷レポート · 研究参考用
Methacryloyl chloride → 5,5,5-Trifluoro-4-hydroxy-4-(trifluoromethyl)pentan-2-yl methacrylate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methacryloyl chloride | HCID 13528 | — |
| 反応物 | Methacrylate | HCID 87595 | — |
| 反応物 | 1,1,1-Trifluoro-2-(trifluoromethyl)-2,4-pentanediol | HCID 118191 | — |
| 反応物 | Butyllithium | HCID 178418339 | — |
| 生成物 | 5,5,5-Trifluoro-4-hydroxy-4-(trifluoromethyl)pentan-2-yl methacrylate | HCID 16050138 | — |
反応手順
The title compound was prepared in the same fashion as the above described methacrylate using 142 g (0.63 mol) of 1,1,1-trifluoro-2-trifluoromethyl-2,4-pentanediol, 793 mL (1.27 mol) of n-butyllithium (1.6M in hexane) and 73 g (0.69 mol) of methacryloyl chloride to yield, after distillation at 67° C. at 1.0 mm Hg, 142 g (76%) of the 2° methacrylate as a clear, colorless oil.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06806026B2 |
| 出典データセット | uspto-grants-2004_10 |
| ORD ID | ord-232e23df82c9495bb6de7e97569df490 |
| 出典メモ | uspto-grants-2004_10 |