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Dimethylformamide → 4-(Chlorosulphonyl)benzoyl chloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Dimethylformamide | HCID 6228 | — |
| 反応物 | Oxalyl chloride | HCID 65578 | — |
| 反応物 | 4-(Chlorosulfonyl)benzoic acid | HCID 82385 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | 4-(Chlorosulphonyl)benzoyl chloride | HCID 82024 | — |
反応手順
Oxalyl chloride (2.2 mL) was added to a mixture of 4-(chlorosulfonyl)benzoic acid (0.662 g, 3.0 mmol) in anhydrous dichloromethane (25 mL) followed by one small drop of N,N-dimethylformamide. The mixture was stirred at room temperature overnight. Then the mixture was then concentrated to provide 4-(chlorosulfonyl)benzoyl chloride which was used without additional purification.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08741899B2 |
| 出典データセット | uspto-grants-2014_06 |
| ORD ID | ord-20593f4ad6564e18add7653c732f413a |
| 出典メモ | uspto-grants-2014_06 |