化工社化工社 化学情報印刷レポート · 研究参考用
2-Methoxyphenyl Isothiocyanate → (S)-Methyl 2-(6-(4-(3-(2-methoxyphenyl)thioureido)phenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Methoxyphenyl Isothiocyanate | HCID 520599 | — |
| 反応物 | (S)-Methyl 2-(6-(4-(3-(2-fluorophenyl)thioureido)phenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate | HCID 53303391 | — |
| 反応物 | (S)-Methyl 2-(6-(4-aminophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate | HCID 131731441 | — |
| 生成物 | (S)-Methyl 2-(6-(4-(3-(2-methoxyphenyl)thioureido)phenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate | HCID 131731458 | — |
反応手順
The compound of example 73 was prepared analogous to compound of example 51 by reaction of compound of example 6 with 2-methoxyphenyl isothiocyanate. The compound of example 73 was used directly without isolation for the preparation of compound of example 74.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08748426B2 |
| 出典データセット | uspto-grants-2014_06 |
| ORD ID | ord-58f9c67de593426cbe93335a3fd1ab53 |
| 出典メモ | uspto-grants-2014_06 |