化工社化工社 化学情報印刷レポート · 研究参考用
(1,1'-Biphenyl)-4-sulfonic acid → (1,1'-Biphenyl)-4-sulphonyl chloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | (1,1'-Biphenyl)-4-sulfonic acid | HCID 16673 | — |
| 反応物 | Phosphorus pentachloride | HCID 24819 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | (1,1'-Biphenyl)-4-sulphonyl chloride | HCID 74192 | — |
反応手順
4-Biphenyl sulfonic acid (2.4 g, 10 mmol) was heated to 100 C with phosphorus pentachloride (2.1 g, 10 mmol) overnight. The reaction was cooled to RT, diluted with water, filtered and washed with water. The solid was then triturated with EtOAc-ether and the beige solid was used in the next reaction without further purification.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06562842B2 |
| 出典データセット | uspto-grants-2003_05 |
| ORD ID | ord-7f8661eeb564456787d1f3625db9a69e |
| 出典メモ | uspto-grants-2003_05 |