化工社化工社 化学情報印刷レポート · 研究参考用
5-Bromoisoindoline → (2,4-Bis-benzyloxy-5-isopropenyl-phenyl)-(5-bromo-1,3-dihydro-isoindol-2-yl)-methanone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 5-Bromoisoindoline | HCID 14795871 | — |
| 反応物 | 2,4-Bis(benzyloxy)-5-isopropenylbenzoic acid | HCID 49864016 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | (2,4-Bis-benzyloxy-5-isopropenyl-phenyl)-(5-bromo-1,3-dihydro-isoindol-2-yl)-methanone | HCID 46915776 | — |
反応手順
Coupling of 2,4-bis-benzyloxy-5-isopropenyl-benzoic acid (5.0 g, 13.4 mmol) (Preparation B9) and 5-bromo-2,3-dihydro-1H-isoindole (Preparation C20) was completed according to method A4, using CH2Cl2 as the reaction solvent to give the title compound (8.34 g) as a beige solid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08530469B2 |
| 出典データセット | uspto-grants-2013_09 |
| ORD ID | ord-cef9f9e57d31466583e2722ebf376fbb |
| 出典メモ | uspto-grants-2013_09 |