Water → 4-(Trimethylsilyl)phenol

HRID 434396

反応式

HRID 434396 の反応式
[CH3:1][Si:2]([CH3:15])([CH3:14])[C:3]1[CH:13]=[CH:12][C:6]([O:7][Si](C)(C)C)=[CH:5][CH:4]=1.O>C(O)C.Cl>[CH3:1][Si:2]([CH3:15])([CH3:14])[C:3]1[CH:13]=[CH:12][C:6]([OH:7])=[CH:5][CH:4]=1

参加物

5

反応物 2

HCID 962WaterHCID 262890Trimethyl{4-[(trimethylsilyl)oxy]phenyl}silane

生成物 1

HCID 257324-(Trimethylsilyl)phenol収率 93.4%

試薬・触媒・溶媒 2

HCID 313Hydrochloric Acid触媒HCID 702Ethanol溶媒

実験手順

28.7 g p-trimethylsilylphenoxytrimethylsilane was dissolved in 9 ml 95 percent ethyl alcohol. One drop of concentrated hydrochloric acid and 4 ml water were added, and the mixture was shaked for 5 minutes. After standing for another 15 minutes, the mixture was washed two times with 30 ml water and separated. The organic phase was poured into a crystallizing dish; p-trimethylsilylphenol crystallized out as white needles. After drying overnight in vacuo, 18.7 g of product was obtained (mp 76 degrees Celsius).

後処理

  1. waitAfter standing for another 15 minutes
  2. washthe mixture was washed two times with 30 ml water
  3. customseparated
  4. additionThe organic phase was poured into a crystallizing dish
  5. customp-trimethylsilylphenol crystallized out as white needles
  6. customAfter drying overnight in vacuo

出典と根拠

ORDレコード
ord-45792f8230c445798738aae519ee22a8
出典データセット
uspto-grants-1983_08
特許番号
US04396704

関連ノート

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