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HRID 434530作成日:2026年10月24日

Aniline → N-phenylcarbamoyl chloride

https://huagongshe.com/ja/reaction/434530

反応式

関与物質

役割名称HCID仕込み量
反応物AnilineHCID 6115—
反応物PhosgeneHCID 6371—
溶媒TolueneHCID 1140—
生成物N-phenylcarbamoyl chlorideHCID 576741—

反応手順

The intermediate is then reacted with a secondary amine in an aprotic solvent such as toluene at temperatures from room temperature or below up to the boiling point of the solvent. An example of this process is the reaction of phosgene with aniline to yield the intermediate N-(phenyl)carbamyl chloride which is then reacted with N-benzyl-n-butylamine to yield 1-benzyl-1-(n-butyl)-3-(phenyl)urea.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US04397868
出典データセットuspto-grants-1983_08
ORD IDord-e87810831aea4dcca6a2fde26a49ebcc
出典メモuspto-grants-1983_08