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Aniline → N-phenylcarbamoyl chloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Aniline | HCID 6115 | — |
| 反応物 | Phosgene | HCID 6371 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | N-phenylcarbamoyl chloride | HCID 576741 | — |
反応手順
The intermediate is then reacted with a secondary amine in an aprotic solvent such as toluene at temperatures from room temperature or below up to the boiling point of the solvent. An example of this process is the reaction of phosgene with aniline to yield the intermediate N-(phenyl)carbamyl chloride which is then reacted with N-benzyl-n-butylamine to yield 1-benzyl-1-(n-butyl)-3-(phenyl)urea.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04397868 |
| 出典データセット | uspto-grants-1983_08 |
| ORD ID | ord-e87810831aea4dcca6a2fde26a49ebcc |
| 出典メモ | uspto-grants-1983_08 |