Ethanol → Ethyl 7-methoxy-9-oxoxanthene-2-carboxylate

HRID 435999

反応式

HRID 435999 の反応式
[CH3:1][O:2][C:3]1[CH:16]=[C:15]2[C:6]([O:7][C:8]3[CH:9]=[CH:10][C:11]([C:18]([OH:20])=[O:19])=[CH:12][C:13]=3[C:14]2=[O:17])=[CH:5][CH:4]=1.[CH2:21](O)[CH3:22]>S(=O)(=O)(O)O>[CH3:1][O:2][C:3]1[CH:16]=[C:15]2[C:6]([O:7][C:8]3[CH:9]=[CH:10][C:11]([C:18]([O:20][CH2:21][CH3:22])=[O:19])=[CH:12][C:13]=3[C:14]2=[O:17])=[CH:5][CH:4]=1

参加物

4

反応物 2

HCID 702EthanolHCID 1931602-Carboxy-7-methoxyxanthen-9-one

生成物 1

HCID 21455094Ethyl 7-methoxy-9-oxoxanthene-2-carboxylate収率 84%

試薬・触媒・溶媒 1

HCID 1118Sulfuric Acid溶媒

実験手順

A mixture of 7-methoxy-9-oxoxanthene-2-carboxylic acid in ethanol (100ml) and concentrated sulfuric acid (10 ml) was refluxed under nitrogen for 24 hours. The reaction mixture was concentrated and cooled. The product, which precipitated, was filtered off and recrystallized from ethanol to give white crystals (2.53g, 84%), mp. 170°-172° C.

後処理

  1. temperaturewas refluxed under nitrogen for 24 hours
  2. concentrationThe reaction mixture was concentrated
  3. temperaturecooled
  4. customThe product, which precipitated
  5. filtrationwas filtered off
  6. customrecrystallized from ethanol

出典と根拠

ORDレコード
ord-675d50573a774e7fad237b71e5dc3df1
出典データセット
uspto-grants-1977_02
特許番号
US04007205

関連ノート

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