化工社化工社 化学情報印刷レポート · 研究参考用
Ethylene Oxide → 4-acetamino-3-methyl-N-(beta-hydroxyethyl)-N-ethylaniline
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ethylene Oxide | HCID 6354 | — |
| 反応物 | 4-Acetamino-3-methyl-N-ethylaniline | HCID 21452831 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | 4-acetamino-3-methyl-N-(beta-hydroxyethyl)-N-ethylaniline | HCID 21452837 | — |
反応手順
15.2g (0.08 mole) of 4-acetamino-3-methyl-N-ethylaniline obtained in Example 1, Part C, 4.2g (0.09 mole) of ethylene oxide and 50ml of ethanol were fed into an autoclave and reacted for 1 hour at 120° to 130° C in the closed autoclave. Thereafter, ethanol was distilled off to obtain crystals of 4-acetamino-3-methyl-N-(β-hydroxyethyl)-N-ethylaniline. The crystals were recrystallized from ethyl acetate to obtain 18.5g of white crystals.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04009205 |
| 出典データセット | uspto-grants-1977_02 |
| ORD ID | ord-f605f6d338414cef8d67e0b2cef64a81 |
| 出典メモ | uspto-grants-1977_02 |