関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Ethanolamine | HCID 700 | — |
| 反応物 | 1-Isothiocyanato-2,4-dimethylbenzene | HCID 142386 | — |
| 溶媒 | Acetone | HCID 180 | — |
| 生成物 | 1-(2-Hydroxyethyl)-3-(2,4-xylyl)-2-thiourea | HCID 1810978 | — |
反応手順
To 20 g. (0.12 mole) of 2,4-dimethylphenylisothiocyanate in 30 ml. of acetone was added dropwise 10 g. (0.16 mole) of ethanolamine in 20 ml. acetone. The solution was refluxed 1 hour then cooled to 4° C., to give crystals which were filtered off, washed with cold ethanol and dried to afford 1-(2,4-dimethylphenyl)-3-(2-hydroxyethyl)-thiourea, 16.8 g. (54% yield) of white crystals m.p. 137.5°-139° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04009284 |
|---|
| 出典データセット | uspto-grants-1977_02 |
|---|
| ORD ID | ord-c01a8d07e63c459a940590ebb0e0ec72 |
|---|
| 出典メモ | uspto-grants-1977_02 |
|---|
