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Phenyl Isothiocyanate → 1-[4-(2-Acetylhydrazino)phenyl]-3-phenylthiourea
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Phenyl Isothiocyanate | HCID 7673 | — |
| 反応物 | Acetic acid, 2-(4-aminophenyl)hydrazide | HCID 81068 | — |
| 溶媒 | Acetonitrile | HCID 6342 | — |
| 生成物 | 1-[4-(2-Acetylhydrazino)phenyl]-3-phenylthiourea | HCID 21427808 | — |
反応手順
1-Acetyl-2-(4-aminophenyl)hydrazine (8.25 g, 0.05 mole) and phenyl isothiocyanate (6.8 g, 0.05 mole) were suspended in acetonitrile (100 ml). The resulting mixture was heated at reflux with stirring for 5 minutes. The product separated from solution as a white solid. After chilling, the product was removed from the reaction mixture by filtration and washed thoroughly with ether. Yield 14.5 g (96%), m.p. 205°-207° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04030925 |
| 出典データセット | uspto-grants-1977_06 |
| ORD ID | ord-a7b5c2b53aa04f22ac27f81cac58c183 |
| 出典メモ | uspto-grants-1977_06 |