化工社化工社 化学情報印刷レポート · 研究参考用
Stannous Chloride → 4-Aminothiophene-2-carboxylic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Stannous Chloride | HCID 24479 | — |
| 反応物 | 4-Nitrothiophene-2-carboxylic acid | HCID 268680 | — |
| 溶媒 | Hydrochloric Acid | HCID 313 | — |
| 生成物 | 4-Aminothiophene-2-carboxylic acid | HCID 6456065 | 72.3% |
反応手順
4-Nitro-2-thiophenecarboxylic acid (1 g, 5.7 mmol) was added with stirring to a solution of SnCl2. 2H2O (3.25 g, 14.4 mmol) in concentrated HCl (10 ml). The mixture was stirred for 6 hours at ambient temperature and purified by subjecting to chromatography on HP20SS resin, using water as eluant, to give the title compound (0.59 g, 71%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05519015 |
| 出典データセット | uspto-grants-1996_05 |
| ORD ID | ord-98016bcfbf334080811ded153d6acb72 |
| 出典メモ | uspto-grants-1996_05 |